发明名称 METHOD FOR REDUCING SCARRING DURING WOUND HEALING USING ANTISENSE COMPOUNDS DIRECTED TO CTGF
摘要 This invention provides a method for reducing hypertropic scarring resulting from dermal wound healing in a subject in need which comprises administering to the subject an antisense oligonucleotide which inhibits expression of connective tissue growth factor (CTGF) in an amount effective to inhibit expression of CTGF and thereby reduce hypertrophic scarring.
申请公布号 EP2334319(A4) 申请公布日期 2013.01.09
申请号 EP20090812035 申请日期 2009.08.26
申请人 EXCALIARD PHARMACEUTICALS, INC.;NORTHWESTERN UNIVERSITY;ISIS PHARMACEUTICALS, INC. 发明人 DEAN, NICOLAS, M.;MUSTOE, THOMAS, A.;SISCO, MARK;KRYGER, ZOL;BENNET, FRANK, C.
分类号 A61K38/18;A61K31/7105 主分类号 A61K38/18
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