DEVICES AND METHODS FOR REDUCING RADIOLYSIS OF RADIOLABELED COMPOUNDS

摘要

Disclosed are devices and methods for reducing radiolysis of radiopharmaceuticals during filtration, concentration and purification. The devices comprises two or more confining geometry having a cross-section dimension below the beta(+) or beta(-) range of the radioisotope in use, when containing the radioisotope, and configured in such a way that neighboring geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the confining geometries when containing the radioisotope. Methods of filtration of radioisotope containing mixtures are also disclosed.