发明名称 |
INORGANIC SALT COMPLEXES OF VILDAGLIPTIN |
摘要 |
The present invention relates to the use of novel vildagliptin complexes for the manufacture of high purity vildagliptin of Formula I and/or pharmaceutical acceptable salts thereof. Further objects of the present invention are pharmaceutically acceptable complexes of vildagliptin and/or amorphous and crystalline forms, anhydrous forms, amorphous and crystalline hydrates, amorphous and crystalline solvates of the complexes and a process for the preparation thereof. Another object of the present invention is the high purity vildagliptin and pharmaceutically acceptable salts thereof prepared form the vildagliptin complexes of the present invention, a process for the preparation thereof and pharmaceutical compositions containing vildagliptin base, pharmaceutically acceptable salts and/or complexes and use thereof for the treatment of type 2 diabetes (NIDDM). The present invention provides pharmaceutically advantageous high purity vildagliptin complexes.
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申请公布号 |
US2013005790(A1) |
申请公布日期 |
2013.01.03 |
申请号 |
US201013500356 |
申请日期 |
2010.10.07 |
申请人 |
MRAVIK ANDRAS;KOEHEGYI IMRE;PONGO LASZLO;VOLK BALAZS;NEMETH GABOR;BARKOCZY JOZSEF;NAGY KALMAN;RUZSICS GYOERGY;BRODA JUDIT;DANCSO ANDRAS;KESZTHELYI ADRIENN;DEBRECZENI JOZSEF |
发明人 |
MRAVIK ANDRAS;KOEHEGYI IMRE;PONGO LASZLO;VOLK BALAZS;NEMETH GABOR;BARKOCZY JOZSEF;NAGY KALMAN;RUZSICS GYOERGY;BRODA JUDIT;DANCSO ANDRAS;KESZTHELYI ADRIENN;DEBRECZENI JOZSEF |
分类号 |
C07D207/16;A61K31/40;A61P3/10 |
主分类号 |
C07D207/16 |
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