Provided are macrocyclic compounds having a macrocyclic core which has at least one macrocyclic donor and at least one pendant group which has at least one donor group. The macrocyclic compounds can be complexed to Fe(II) and Ni(II). The macrocyclic compounds can be used in imaging methods. For example, the compounds can be used MRI paraCEST contrast agents.
申请公布号
WO2012155076(A3)
申请公布日期
2013.01.03
申请号
WO2012US37590
申请日期
2012.05.11
申请人
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;MORROW, JANET;TSITOVITCH, PAVEL;DORAZIO, SARINA;OLATUNDE, ABIOLA