发明名称 |
Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity |
摘要 |
In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject. and/or for the treatment of an immune-related disorder, including treating and preventing infection by modulating innate immunity. Also provided are an agent reactive with the peptide, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the recombinant nucleic acid construct, and a method of producing the peptide using the host cell. The present invention further provides a method for treating and/or preventing infection in a subject by administering the peptide of the invention to the subject, thereby modulating innate immunity in the subject. Additionally, the present invention provides a method for predicting whether a subject would be responsive to treatment with a peptide of the invention. |
申请公布号 |
EP2447367(A3) |
申请公布日期 |
2013.01.02 |
申请号 |
EP20110182635 |
申请日期 |
2006.10.04 |
申请人 |
INIMEX PHARMACEUTICALS INC. |
发明人 |
DONINI, OREOLA;ROZEK, ANNETT;LENTZ, SHANNON WAYNE |
分类号 |
C12N15/11;A61K38/08;A61K38/10;A61P31/00;A61P33/00;A61P37/02;C07K5/08;C07K5/103;C07K5/11;C07K7/06;C07K7/08;C07K16/00;C12N1/21;C12N15/63;C12P21/02;C12Q1/37 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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