发明名称 4-dimethylaminobutyric acid derivatives
摘要 This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formula wherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors.
申请公布号 US8344027(B2) 申请公布日期 2013.01.01
申请号 US20090430934 申请日期 2009.04.28
申请人 HOFFMANN-LA ROCHE INC.;ANDJELKOVIC MIRJANA;CECCARELLI SIMONA M.;CHOMIENNE ODILE;KAPLAN GERALD LEWIS;MATTEI PATRIZIO;TILLEY JEFFERSON WRIGHT 发明人 ANDJELKOVIC MIRJANA;CECCARELLI SIMONA M.;CHOMIENNE ODILE;KAPLAN GERALD LEWIS;MATTEI PATRIZIO;TILLEY JEFFERSON WRIGHT
分类号 A61K31/195;C07C229/00 主分类号 A61K31/195
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