发明名称 |
HIGH CONCENTRATION ANTIBODY-CONTAINING LIQUID FORMULATION |
摘要 |
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine. |
申请公布号 |
SI2238985(T1) |
申请公布日期 |
2012.12.31 |
申请号 |
SI20080030806T |
申请日期 |
2008.12.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG |
发明人 |
MORICHIKA TOSHIYUKI;KAMEOKA DAISUKE;IMAEDA YOSHIMI;MAEDA TERUTOSHI;STAUCH OLIVER BORIS |
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