METHODS AND SYSTEMS FOR THE RAPID CHARACTERIZATION OF FUNCTIONAL BIOLOGICAL MOLECULES
摘要
In one non-limiting aspect, the invention provides a method for detecting the quality of a biological molecule comprising forming a first mixture of ingredients comprising: (i) a first binding agent that specifically binds to a tag, wherein the first binding agent is attached to a solid support; (ii) a decoy comprising a first portion comprising the tag attached to a second portion comprising an anchor; (iii) a sensor attached to a second binding agent that specifically binds to the anchor; and (iv) a sample suspected of containing a high quality biological molecule comprising a tag, wherein the tag of the high quality biological molecule is accessible; allowing interaction of the ingredients such that the sensor provides an output signal
申请公布号
WO2012177755(A1)
申请公布日期
2012.12.27
申请号
WO2012US43341
申请日期
2012.06.20
申请人
BIOSCALE, INC.;ALDERMAN, EDWARD, MARSHALL;MASTERS, BRETT, PETER;MILLER, MICHAEL, FRANCIS;DICKERSON, WILLIAM, MATTHEW
发明人
ALDERMAN, EDWARD, MARSHALL;MASTERS, BRETT, PETER;MILLER, MICHAEL, FRANCIS;DICKERSON, WILLIAM, MATTHEW