| 发明名称 |
SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-{3-[CIS-HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL]PROPOXY}BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a novel industrial synthesis process for a benzamide derivative (1), and a use as a medicine. <P>SOLUTION: The present invention relates to the industrial synthesis process which yields a compound of formula (1) with satisfactory purity from the pharmaceutical point of view and in an effective yield from the industrial point of view, as well as crystalline form I thereof and the use thereof as a medicine. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2012254982(A) |
申请公布日期 |
2012.12.27 |
| 申请号 |
JP20120129440 |
申请日期 |
2012.06.07 |
| 申请人 |
LAB SERVIER |
发明人 |
ROBERT NICOLAS;LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;GAILLARD MARINA;MEUNIER LOIC;LETELLIER PHILIPPE;BOIRET MATHIEU |
| 分类号 |
C07D209/52;A61K31/403;A61P3/04;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/28 |
主分类号 |
C07D209/52 |
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