| 摘要 |
Disclosed is a peptide having an ability to bind to an HLA-A*1101 molecule, and an ability to induce a cytotoxic T lymphocyte (CTL), the peptide consisting of the amino acid sequence Thr Gly Val Lys Pro Phe Gln Cys Lys, in which one to five amino acid(s) are substituted. Also disclosed are peptide dimers, the use of the peptides in the manufacture of a medicament, expression vectors, pharmaceutical compositions, WT1-specific cytotoxic T lymphocyte, wherein said cytotoxic T lymphocyte has been induced by the peptide and methods for induction of WT1-specific cytotoxic T lymphocytes. |
