发明名称 |
REGULATION OF MACROPHAGE ACTIVATION USING MIR-125B |
摘要 |
The present disclosure relates to regulation of macrophage activation by delivering of miRNAs, for example miR-125b or anti-miR-125b, to macrophages. For example, in some embodiments, macrophage activation can be elevated or reduced by administering miR-125b or anti-miR-125b oligonucleotides. Also disclosed are methods for promoting T cell activation and method for treating various disorders such as tumor and autoimmune diseases.
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申请公布号 |
US2012322854(A1) |
申请公布日期 |
2012.12.20 |
申请号 |
US201213526347 |
申请日期 |
2012.06.18 |
申请人 |
CHAUDHURI AADEL;SO ALEX STEVEN;BALTIMORE DAVID;O'CONNELL RYAN M.;CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
CHAUDHURI AADEL;SO ALEX STEVEN;BALTIMORE DAVID;O'CONNELL RYAN M. |
分类号 |
A61K31/7088;A61P1/00;A61P19/02;A61P25/00 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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地址 |
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