METHODS FOR TREATING OR PREVENTING GRAFT VERSUS HOST DISEASE
摘要
A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat or prevent GVHD in the host subject following infusion of the graft into the subject. After the contacting of the graft with the Myxoma Virus, the method comprises transplanting the virus-treated graft into the subject.
申请公布号
WO2012171007(A2)
申请公布日期
2012.12.13
申请号
WO2012US41905
申请日期
2012.06.11
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;MCFADDEN, DOUGLAS, GRANT;BARTEE, ERIC, CARTER;COGLE, CHRISTOPHER, R.
发明人
MCFADDEN, DOUGLAS, GRANT;BARTEE, ERIC, CARTER;COGLE, CHRISTOPHER, R.