| 发明名称 |
COMPOSITIONS AND METHODS FOR ENHANCED PARVOVIRUS TRANSDUCTION |
| 摘要 |
<p>The present invention provides methods and compositions for enhanced transduction of an adeno-associated virus (AAV) vector comprising a heterologous nucleic acid of interest wherein the AAV vector genome is oversized relative to a wild type AAV genome by employing a proteasome inhibitor.</p> |
| 申请公布号 |
EP2531604(A2) |
申请公布日期 |
2012.12.12 |
| 申请号 |
EP20110740407 |
申请日期 |
2011.02.04 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
MONAHAN, PAUL E.;SAMULSKI, RICHARD JUDE |
| 分类号 |
C12N15/864;A61K31/517;A61K48/00;A61P7/04;A61P21/00;C12N15/33 |
主分类号 |
C12N15/864 |
| 代理机构 |
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