ORAL CONTROLLED RELEASE COMPOSITIONS COMPRISING VITAMIN D COMPOUND AND WAXY CARRIER
摘要
A stable, controlled release formulation for oral dosing of vitamin D compounds is disclosed. The formulation is prepared by incorporating one or more vitamin D compounds into a solid or semi-solid mixture of waxy materials. Oral dosage forms can be prepared by melt-blending the components described herein and filling gelatin capsules with the formulation.
申请公布号
EP2148661(B1)
申请公布日期
2012.12.12
申请号
EP20080746908
申请日期
2008.04.25
申请人
CYTOCHROMA INC.;PROVENTIV THERAPEUTICS, LLC
发明人
BISHOP, CHARLES, W.;TABASH, SAMIR, P.;AGUDOAWU, SAMMY, A.;WHITE, JAY, A.;CRAWFORD, KEITH, H.;MESSNER, ERIC, J.;PETKOVICH, P. MARTIN