RADIATION SENSITIZATION AGENTS FOR PROSTATE CANCER
摘要
Compositions and methods are provided for sensitizing neoplastic cells to radiotherapy. The invention provides aptamer-inhibitory nucleic acid chimeras that selectively inliibit the expression of radiosensitizing genes in neoplastic cells expressing a cell surface molecule that binds the aptamer.
申请公布号
WO2012012710(A3)
申请公布日期
2012.12.06
申请号
WO2011US44997
申请日期
2011.07.22
申请人
THE JOHNS HOPKINS UNIVERSITY;LUPOLD, SHAWN, EDWARD;DEWEESE, THEODORE, L.;NI, XIAOHUA;ZHANG, YONGGANG