摘要 |
In one aspect, the invention relates to compounds having the formula: (I) where R1, R2, R3, a, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |
申请人 |
THERAVANCE, INC.;FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE |
发明人 |
FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE |