发明名称 NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: (I) where R1, R2, R3, a, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 WO2012166389(A1) 申请公布日期 2012.12.06
申请号 WO2012US38517 申请日期 2012.05.18
申请人 THERAVANCE, INC.;FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE 发明人 FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE
分类号 C07C233/00;A61P9/00 主分类号 C07C233/00
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