发明名称 |
Compositions for importing biologically active molecules into cells |
摘要 |
The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy to regulate and/or eradicate systemic inflammatory response syndromes such as endotoxic shock.
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申请公布号 |
US8324148(B2) |
申请公布日期 |
2012.12.04 |
申请号 |
US20020319316 |
申请日期 |
2002.12.13 |
申请人 |
HAWIGER JACK J.;ROBINSON DANIEL;VEACH RUTH ANN;LIU XUE YAN;LIU DANYA;DOWNS SHEILA;COLLINS ROBERT D.;LIN YAO-ZHONG;VANDERBILT UNIVERSITY |
发明人 |
HAWIGER JACK J.;ROBINSON DANIEL;VEACH RUTH ANN;LIU XUE YAN;LIU DANYA;DOWNS SHEILA;COLLINS ROBERT D.;LIN YAO-ZHONG |
分类号 |
A61K38/00;A61K31/20;A61K31/70;A61K38/04;A61K38/16;A61K38/17;A61K39/00;A61K47/48;A61P7/00;A61P29/00;A61P31/04;C07K14/475;C07K14/50;C12N15/62;C12N15/87 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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