IGF-1R-BINDING PEPTIDE

摘要

Provided are: a substance capable of binding to IGF-1R in a specific manner and with high affinity; and a medicinal agent comprising the substance. A peptide which comprises at least the amino acid sequence represented by formula (1) and has 8-50 amino acid residues. Phe-X1-X2-X3-X4-X5-X6-X7 (1) (wherein X1 represents Tyr, Trp, Phe or His; X2 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys; X3 represents Met, Leu, Ile, Val, Ala, Phe, Tyr, Trp or Cys; X4 represents Leu, Ile, Val or Met; X5 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg; X6 represents Arg, Lys, His, Asn, Gln, Ser, Thr, Asp, Glu or Ala; and X7 represents Leu, Ile, Val or Met).