发明名称 |
BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID |
摘要 |
<p>The present invention encompasses a recombinant bacterium comprising a regulated rfaH nucleic acid, as well as a vaccine comprising said recombinant bacterium. Other embodiments of the present invention encompass a recombinant bacterium comprising a regulated rfaH nucleic acid and a regulated rfc nucleic acid, while additional embodiments encompass a recombinant bacterium comprising a regulated rfaH nucleic acid and at least one nucleic acid encoding at least one exogenous antigen.</p> |
申请公布号 |
EP2526185(A1) |
申请公布日期 |
2012.11.28 |
申请号 |
EP20110735255 |
申请日期 |
2011.01.21 |
申请人 |
ARIZONA BOARD OF REGENTS FOR AND ON BEHALF ARIZONA STATE UNIVERSITY |
发明人 |
CURTISS, III, ROY;KONG, QINGKE |
分类号 |
C12N1/00;A61K39/09;A61K39/112;C07K14/255;C07K14/315;C12N1/36;C12N9/10 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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