发明名称 Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy
摘要 Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
申请公布号 US8318692(B2) 申请公布日期 2012.11.27
申请号 US201113005568 申请日期 2011.01.13
申请人 DONALD CARLTON D. 发明人 DONALD CARLTON D.
分类号 A61K31/70;C07H21/04 主分类号 A61K31/70
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