发明名称 N-acyl amino acid derivatives, a method for the preparation thereof, a pharmaceutical composition and use thereof as anti-allergic, anti-inflammatory and hypolipidemic agents
摘要 The present invention relates to N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof wherein n is 2 or 3; and R1 represents or pharmaceutically acceptable salts thereof, to novel processes for preparing the same, to use thereof as anti-allergic, anti-anaphylactic, anti-inflammatory and hypolipidemic agents as well as to a pharmaceutical composition comprising the indicated compounds in an efficient amount and to a method for treating allergic and inflammatory diseases and lipid metabolism disorders: bronchial asthma, allergic rhinitis, pollinoses, seasonal and year-round rhinitis, allergic pneumonitis, atopic dermatitis, psoriasis, urticaria, allergic (including anaphylactic) reactions to insect stings and medicaments, cold allergy, allergic conjunctivitis, atherosclerosis, obesity, ischemic heart and cerebral disease, myocardial infarction and stroke.
申请公布号 US8318950(B2) 申请公布日期 2012.11.27
申请号 US20100764515 申请日期 2010.04.21
申请人 NEBOLSIN VLADIMIR EVGENIEVICH;KROMOVA TATYANA ALEXANDROVNA;ZHELTUKHINA GALINA ALEXANDROVNA ALEXANDROVNA;KOVALEVA VIOLETTA LEONIDOVNA;OTKRYTOE AKTSIONERNOE OBSCHESTVO-OTECHESTVENNYE LEKARSTVA 发明人 NEBOLSIN VLADIMIR EVGENIEVICH;KROMOVA TATYANA ALEXANDROVNA;ZHELTUKHINA GALINA ALEXANDROVNA ALEXANDROVNA;KOVALEVA VIOLETTA LEONIDOVNA
分类号 C07D233/64;C07D209/12 主分类号 C07D233/64
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