发明名称 |
COMPOUNDS INHIBITING CD95 SIGNALING FOR THE TREATMENT OF PANCREATIC CANCER |
摘要 |
The present invention is concerned with compounds inhibiting CD95 signaling in pancreatic cancer cells. Furthermore, contemplated by the current invention are medicaments comprising such a compound for the prevention and/or treatment of pancreatic cancer as well as the use of such a compound for the manufacture of a medicament for the prevention and/or treatment of pancreatic cancer, the prevention of migration of cancer cells, and/or the prevention and/or treatment of an inflammatory reaction. The present invention also refers to a method for the identification of a compound inhibiting CD95 signaling, as we to a method for the manufacture of a medicament comprising the steps of the method for the identification of a compound inhibiting CD95 signaling and the further step of formulating the inhibiting compound as a medicament.
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申请公布号 |
US2012294856(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
US201013509592 |
申请日期 |
2010.11.15 |
申请人 |
MARTIN-VILALBA ANA;HERHAUS PETER;SANCHO-MARTINEZ IGNACIO;KLEBER SUSANNE;WELSCH THILO;RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG;DEUTSCHES KREBSFORSCHUNGSZENTRUM |
发明人 |
MARTIN-VILALBA ANA;HERHAUS PETER;SANCHO-MARTINEZ IGNACIO;KLEBER SUSANNE;WELSCH THILO |
分类号 |
A61K39/395;A61K31/7105;A61K31/713;A61P35/00;C07H21/02;C07H21/04;C07K16/18;C07K19/00;C12Q1/02;C12Q1/68;C40B30/04;G01N33/566;G01N33/573 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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