<p>A sensor for measuring oxygen concentration in a tissue or an organ of a subject is provided. The sensor includes a sensory element comprising at least one paramagnetic spin probe compound encapsulated in a biocompatible oxygen permeable material. A barrier layer partially covers the sensory element and is comprised of at least one biocompatible oxygen impermeable material. Oxygen concentration data may be acquired by applying the sensor to the tissue or the organ of the subject, and subsequently applying a magnetic resonance spectroscopy or imaging technique.</p>
申请公布号
WO2012158812(A1)
申请公布日期
2012.11.22
申请号
WO2012US38166
申请日期
2012.05.16
申请人
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION;KUPPUSAMY, PERIANNAN;RIVERA, BRIAN;ETESHOLA, EDWARD;MEENAKSHISUNDARAM, GURUGUHAN