发明名称 |
COMPOSITIONS AND METHODS FOR THE ALTERATION OF XLHED PHENOTYPES |
摘要 |
The invention relates to methods for the temporal administration of EDA agonists, in particular EDI200, which correlate to optimal therapeutic response windows required for the formation of any EDA-dependent structures such as ectodermal appendages. Use of the methods described allow for the design of targeted therapeutic dosing and administration regimens in order to correct or alter abnormal phenotypes associated with genetic disorders, in particular, XLHED. |
申请公布号 |
CA2835882(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
CA20122835882 |
申请日期 |
2012.05.10 |
申请人 |
EDIMER PHARMACEUTICALS, INC. |
发明人 |
SCHNEIDER, PASCAL;KOWALCZYK, CHRISTINE |
分类号 |
A61K47/48;C07K14/705;C07K19/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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