| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide ligands used in affinity chromatography for the fast and economical purification of a target molecule in high yield. <P>SOLUTION: The alkaline-stable chromatography ligand comprises two or more B domains or two or more Z domains of Staphylococcus protein A (SpA), or a functional fragment or variant thereof, where the two or more B domains or two or more Z domains are attached to a chromatography resin at more than one site on the resin. <P>COPYRIGHT: (C)2013,JPO&INPIT |
