发明名称 NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY
摘要 <p>An object of the present invention is to synthesize a novel 1,2,3,4-tetrahydroquinoxaline derivative represented by formula (1) and to find a pharmacological action of the derivative. In the formula, the R 1 represents a halogen, an alkyl, cycloalkyl, aryl or heterocyclic group, or the like; p represents 0 to 5; R 2 represents a halogen, an alkyl, hydroxyl or alkoxy group, or the like; q represents 0 to 2; R 3 represents hydrogen, an alkyl, alkenyl, alkylcarbonyl or arylcarbonyl group, or the like; R 4 and R 5 independently represent hydrogen, a halogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; R 6 represents hydrogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; A represents an alkylene; R 7 represents OR 8 , NR 8 R 9 , SR 8 , S(O)R 8 , S(O) 2 R 8 ; and X represents O or S.</p>
申请公布号 PT1995242(E) 申请公布日期 2012.11.22
申请号 PT20070738592T 申请日期 2007.03.14
申请人 SANTEN PHARMACEUTICAL CO., LTD 发明人 KENJI KAWASHIMA;MINORU YAMAMOTO;MAMORU MATSUDA;TOSHIYUKI MORI;MASATOMO KATO;MIWA TAKAI;MASATO NAGATSUKA;SACHIKO KOBAYASHI
分类号 C07D417/14;C07D241/44;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12 主分类号 C07D417/14
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