发明名称 ANTI-αVβ6 ANTIBODY
摘要 <P>PROBLEM TO BE SOLVED: To obtain an antibody that specifically binds to &alpha;<SB POS="POST">v</SB>&beta;<SB POS="POST">6</SB>, but does not bind to other &alpha;<SB POS="POST">v</SB>integrins or non-specific integrins. <P>SOLUTION: The antibody specifically binds to &alpha;<SB POS="POST">v</SB>&beta;<SB POS="POST">6</SB>, but does not bind to other &alpha;<SB POS="POST">v</SB>integrins or non-specific integrins. Also, the invention provides a method for treating mammals having or at risk of having &alpha;<SB POS="POST">v</SB>&beta;<SB POS="POST">6</SB>-mediated diseases, or a method for diagnosing the &alpha;<SB POS="POST">v</SB>&beta;<SB POS="POST">6</SB>-mediated diseases. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012228269(A) 申请公布日期 2012.11.22
申请号 JP20120177349 申请日期 2012.08.09
申请人 BIOGEN IDEC MA INC;REGENTS OF THE UNIV OF CALIFORNIA 发明人 VIOLETTE SHELIA M;WEINREB PAUL H;SIMON KENNETH J;SHEPPARD DEAN;LEONE DIANE R
分类号 C12N15/09;A61K39/395;A61K47/48;A61K51/10;A61P1/16;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P35/00;C07K7/08;C07K14/00;C07K16/18;C07K16/28;C12N;C12N5/10;C12N5/12;C12P21/08;C12Q1/02;G01N33/574;G01N33/68 主分类号 C12N15/09
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