PHOSPHONIUM SALTS ON BASIS OF PYRIDOXINE DERIVATIVES

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to phosphonium salt of pyridoxine derivatives of general formula (I) which may be used in medicine and veterinary science wherein if R1=CH3; R2=CH3; X=H; n=1; R1=CH3; R2=H; X-H; n=1; R1=CH3; R2=CH3; X-CH2P*Ph3; n=2; R,=CH3; R2=H; X=CH2P+Ph3; n=2; R,=CH3; R2=C(CH3)2; X=CH2P+Ph3; n=2. ^ EFFECT: there are presented new compounds with antibacterial activity on Staphylococcus aureus, including multiresistant strains, as well as low toxicity. ^ 1 cl, 1 ex, 1 tbl