LECITHINIZED SUPEROXIDE DISMUTASE COMPOSITION AND A PROCESS FOR ITS PRODUCTION

摘要

To provide a lecithinized superoxide dismutase (PC--SOD) composition useful as a drug material and a process for its production. The PC-SOD composition contains a PC-SOD obtained by substituting at least amino group in a specific SOD with a lecithin moiety represented by the following formula (I), wherein the PC-SOD contains a PC-SOD (A) having an m number of amino groups substituted with the lecithin moieties (wherein m is an integer of from 1 to 4 and averages from 1.5 to 2.4] as a main component, and the PC-SOD (A) consists of a PC-SOD (a1) wherein m = 1, a PC--SOD (a2) wherein m = 2, a PC-SOD (a3) wherein m 3 and a PC-SOD (a4) wherein m = 4. (see formula I)