PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF TUBERCULOSIS AND OTHER INFECTIONS, AND METHOD FOR PRODUCING SAID COMPOSITION

摘要

The invention relates to pharmacology, medicine, veterinary medicine and to the pharmaceutical industry, in particular to a method for producing original composite antimicrobial preparations for parenteral use, said preparations having increased therapeutic effectiveness in the treatment of severe forms of tuberculosis and other infectious inflammatory diseases. The proposed pharmaceutical composition comprises an antibiotic - aminoglycoside or capreomycin and highly dispersed nano-structured silicon dioxide as the active substance. The claimed method for the production of the pharmaceutical composition consists in mixing the antibiotic - aminoglycoside or capreomycin with the highly dispersed nano-structured silicon dioxide, characterized in that the mixture of the above-mentioned substances in ratios of 10:1 to 70:1 by weight, respectively, is subjected to mechanical processing by means of impact-abrading actions to increase the finely dispersed fraction weight portion. The mixture produced is used for preparing injection solutions.