Influenza hemagglutinin and neuraminidase variants

摘要

The present invention relates to a 6:2 reassortant influenza virus, wherein said virus comprises 6 genes encoding regions that encode internal genome segments from A/Ann Arbor/6/60 and 2 genes encoding regions that encode a hemagglutinin polypeptide and a neuraminidase polypeptide, wherein the hemagglutinin polypeptide comprises the amino acid sequence of SEQ ID NO: 11 and the neuraminidase polypeptide comprises the amino acid sequence of SEQ ID NO:12.