| 发明名称 |
ANTICANCER AGENT FOR HEAD AND NECK CANCER AND ESOPHAGEAL CANCER, AND POTENTIATOR |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide: an anticancer agent for a head and neck cancer and an esophageal cancer having excellent effect on the head and neck cancer and the esophageal cancer; and a potentiator enhancing the effect of the anticancer agent on the head and neck cancer and the esophageal cancer. <P>SOLUTION: The anticancer agent for a head and neck cancer or an esophageal cancer includes (a) and (b) as active principles: (a) a double stranded RNA having the RNAi effect on the RECQL1 gene or the WRN gene; and (b) a DNA capable of expressing a double stranded RNA having the RNAi effect on the RECQL1 gene or the WRN gene. The potentiator enhancing the effect of the anticancer agent on a head and neck cancer or an esophageal cancer includes (a) and (b) as active principles: (a) a double stranded RNA having the RNAi effect on the RECQL1 gene or the WRN gene; and (b) a DNA capable of expressing a double stranded RNA having the RNAi effect on the RECQL1 gene or the WRN gene. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2012219085(A) |
申请公布日期 |
2012.11.12 |
| 申请号 |
JP20110089089 |
申请日期 |
2011.04.13 |
| 申请人 |
SHIGA UNIV OF MEDICAL SCIENCE;GENECARE RESEARCH INSTITUTE CO LTD |
发明人 |
CHANO NORIHIRO;SHIMADA TAKETOSHI;FUTAMI KAZUNOBU;FURUICHI YASUHIRO |
| 分类号 |
A61K48/00;A61K31/7105;A61K31/711;A61K38/00;A61K39/395;A61K45/00;A61P35/00;C12N15/09;C12N15/113 |
主分类号 |
A61K48/00 |
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