发明名称 Biomarkers for the Diagnosis of Kidney Graft Rejection
摘要 Methods are provided for determining a transplant category of a subject having a kidney graft. In practicing one aspect of the subject methods, the peptide signature of a non-invasive sample derived from the transplant subject (e.g., a urine sample) is used to determine the subject's transplant category (e.g., acute allograft rejection (AR), stable allograft (STA), BK virus nephropathy (BK), and the like). In other embodiments, a gene expression signature from a biopsy sample from the subject (e.g., mRNA level) is used to determine the subject's transplant category. In certain embodiments both a peptide signature and a gene expression signature are used. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods.
申请公布号 US2012283123(A1) 申请公布日期 2012.11.08
申请号 US201013508013 申请日期 2010.11.24
申请人 SARWAL MINNIE M.;LING BRUCE XUEFENG;SIGDEL TARA;SCHILLING JAMES 发明人 SARWAL MINNIE M.;LING BRUCE XUEFENG;SIGDEL TARA;SCHILLING JAMES
分类号 G01N27/72;C12Q1/68;C40B30/04;C40B40/06 主分类号 G01N27/72
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