发明名称 |
BIOAFFINITY SENSORS BASED ON SURFACE MONOLAYERS |
摘要 |
Methods, systems, devices and materials are disclosed for implementing a bioaffinity sensor having a self-assembled monolayer interface for detection of a target molecule. In one aspect, a sensor device for detecting a target molecule includes a surface capable of attaching a thiol and a molecular monolayer formed on the surface that includes a molecular capture probe having a thiol region, a linear alkanethiol molecule having one thiol region, and a linear alkanedithiol molecule having two thiol regions, in which the molecular capture probe includes a region for receiving a target substance having a complimentary region that couples with the region of the molecular capture probe to generate a detectable signal. |
申请公布号 |
WO2012148516(A2) |
申请公布日期 |
2012.11.01 |
申请号 |
WO2012US23039 |
申请日期 |
2012.01.27 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;WANG, JOSEPH;CAMPUZANO-RUIZ, SUSANA |
发明人 |
WANG, JOSEPH;CAMPUZANO-RUIZ, SUSANA |
分类号 |
G01N33/53;C12Q1/68;G01N27/26;G01N33/553 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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