| 发明名称 |
PHARMACEUTICAL COMPOSITION |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide pharmaceutical compositions that enable the successful delivery of poly(amino acids) such as peptides, peptidomimetics and proteins via oral administration to accomplish the desired therapeutic effect. <P>SOLUTION: The oral pharmaceutical composition in a tablet form comprises: (i) a parathyroid hormone (PTH) or a fragment thereof containing at least an amino acid (1-28); a compound represented by formula I; a disintegrant; and a diluent; wherein the composition has a disintegration time of 80% or more at 20 minutes in gastric media. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2012211159(A) |
申请公布日期 |
2012.11.01 |
| 申请号 |
JP20120135063 |
申请日期 |
2012.06.14 |
| 申请人 |
NOVARTIS AG |
发明人 |
AZRIA MOISE;BATEMAN SIMON DAVID;GHOSH ANASUYA ASHOK;LI SHOUFENG;ROYCE ALAN EDWARD |
| 分类号 |
A61K38/22;A61K9/20;A61K38/23;A61K47/16;A61P19/02;A61P19/10 |
主分类号 |
A61K38/22 |
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