SILICA NANOPARTICLES HAVING FLUORESCENT SUBSTANCE CONFINED THEREIN, AND LABELING AGENT FOR BIOSUBSTANCE

摘要

Provided are silica nanoparticles each having a fluorescent substance confined therein. The silica nanoparticles are characterized in that the surfaces of the silica nanoparticles have been coated with a substance having a bulk refractive index of 1.60-4.00. The silica nanoparticles having a fluorescent substance confined therein have excellent long-term storability. A biosubstance-labeling agent obtained using the silica nanoparticles can be provided.