发明名称 CONSTITUTIVE EXPRESSION OF COSTIMULATORY LIGANDS ON ADOPTIVELY TRANSFERRED T LYMPHOCYTES
摘要 <p>The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen-recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.</p>
申请公布号 EP2141997(B1) 申请公布日期 2012.10.31
申请号 EP20080742463 申请日期 2008.03.31
申请人 MEMORIAL SLOAN-KETTERING CANCER CENTER 发明人 SADELAIN, MICHEL;STEPHAN, MATTHIAS
分类号 A61K39/00 主分类号 A61K39/00
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