发明名称 A buprenorphine transdermal patch for use in the treatment of pain for a dosing interval of at least 7 days
摘要 A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days.
申请公布号 SI2305194(T1) 申请公布日期 2012.10.30
申请号 SI19980030937T 申请日期 1998.02.24
申请人 EURO-CELTIQUE S.A. 发明人 REDER ROBERT F.;GOLDENHEIM PAUL D.;KAIKO ROBERT F.
分类号 A61F13/00;A61K9/22;A61K9/70;A61K31/00;A61K31/485;A61P25/00;A61P29/00 主分类号 A61F13/00
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