发明名称 |
Adhesive pharmaceutical preparation containing bisoprolol |
摘要 |
In the adhesive pharmaceutical preparation of the invention containing bisoprolol, a pressure-sensitive adhesive layer is laminated on one side of the backing. The pressure-sensitive adhesive layer contains a branched monoalcohol having from 12 to 28 carbon atoms, a free base of bisoprolol and a polyisobutylene pressure-sensitive adhesive. Accordingly, compatibility of the polyisobutylene pressure-sensitive adhesive with the free base of bisoprolol can be specifically increased. As a result, not only it becomes possible to increase blending amount of the free base of bisoprolol but also bleed of the free base of bisoprolol from the pressure-sensitive adhesive layer can be suppressed and, what is more, the pressure-sensitive adhesion characteristics sufficient from the practical point of view can be obtained. |
申请公布号 |
US8298572(B2) |
申请公布日期 |
2012.10.30 |
申请号 |
US20060097260 |
申请日期 |
2006.12.13 |
申请人 |
IWAO YOSHIHIRO;OOKUBO KATSUYUKI;OKADA KATSUHIRO;MINAMI KUNIHIRO;YUASA SHUICHIRO;NITTO DENKO CORPORATION;TOA EIYO LTD. |
发明人 |
IWAO YOSHIHIRO;OOKUBO KATSUYUKI;OKADA KATSUHIRO;MINAMI KUNIHIRO;YUASA SHUICHIRO |
分类号 |
A61K9/70;A61K31/045;A61K31/138;A61K47/10;A61K47/32 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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