SYNTHETIC OLIGOSACCHARIDES FOR STAPHYLOCOCCUS VACCINE
摘要
<p>The present invention synthetic oligo-ß-(1?6)-glucosamine structures and a methodology which essentially allows for the synthesis of any oligo-ß-(1?6)-glucosamine species having a definite number of monosaccharide units, including a set pattern of acetylated and non- acetylated residues. The invention further provides antibodies to these synthetic oligo-ß-(1?6)-glucosamines as well as compositions thereof and methods for treating and preventing infections caused by bacteria expressing poly-ß-(1?6)-glucosamines, such as Staphylococcus aureus.</p>
申请公布号
WO2012145626(A1)
申请公布日期
2012.10.26
申请号
WO2012US34449
申请日期
2012.04.20
申请人
ANCORA PHARMACEUTICALS INC.;CAMPBELL, A., STEWART;PLANTE, OBADIAH, J.