| 发明名称 |
PYRIDYL DERIVATIVES AS CFTR MODULATORS |
| 摘要 |
The present invention relates to modulators of ATP-Binding Cassette (ABC) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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| 申请公布号 |
US2012270869(A1) |
申请公布日期 |
2012.10.25 |
| 申请号 |
US201213533326 |
申请日期 |
2012.06.26 |
| 申请人 |
HADIDA RUAH SARA;MILLER MARK;ZHOU JINGLAN;BEAR BRIAN;GROOTENHUIS PETER;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
HADIDA RUAH SARA;MILLER MARK;ZHOU JINGLAN;BEAR BRIAN;GROOTENHUIS PETER |
| 分类号 |
A61K31/443;A61K31/44;A61K31/5377;A61P11/00;A61P17/00;A61P27/02;C07D213/72;C07D405/12;C07D405/14;C07D413/14;G01N21/64 |
主分类号 |
A61K31/443 |
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