发明名称 |
PHARMACEUTICAL COMPOSITIONS WITH ENHANCED STABILITY |
摘要 |
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a peptide agent formed with a strong acid that minimizes or prevents the interaction/reaction between the peptide agent and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof. |
申请公布号 |
EP1984009(B1) |
申请公布日期 |
2012.10.24 |
申请号 |
EP20070718050 |
申请日期 |
2007.01.16 |
申请人 |
QPS, LLC |
发明人 |
LI, YUHUA;CHIEN, BENJAMIN |
分类号 |
A61K38/00;A01N59/16;A61K33/32 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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