发明名称 COLLAGEN HYDROXYLASES
摘要 <p>Prolyl and lysyl hydroxylases isolated from Mimivirus are described. These are able to hydroxylate collagen. Isolated nucleic acids coding for the mentioned hydroxylases are incorporated into suitable vectors and used to express these hydoxylases in host cells, e.g. E. coli. Furthermore a method of manufacturing hydroxylated collagen in a host cell is described. The hydroxylases and the recombinantly expressed hydroxylated collagen are useful in clinical settings and biotechnology applications.</p>
申请公布号 WO2012139866(A1) 申请公布日期 2012.10.18
申请号 WO2012EP55030 申请日期 2012.03.21
申请人 UNIVERSITAET ZUERICH PROREKTORAT MNW;HENNET, THIERRY;RUTSCHMANN, CHRISTOPH;LUTHER, KELVIN 发明人 HENNET, THIERRY;RUTSCHMANN, CHRISTOPH;LUTHER, KELVIN
分类号 C12N9/02;C07K14/78;C12N9/00 主分类号 C12N9/02
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