摘要 |
<P>PROBLEM TO BE SOLVED: To provide stabilization of enzyme activity in an electrochemical biosensor, regarding improvement of the electrochemical biosensor used for measurement of the amount of an analyte in a biological fluid, particularly glucose in a whole blood sample. <P>SOLUTION: A reagent composition containing GDH-PQQ as an enzyme-co-factor and screen-printed on working and counter electrodes of electrochemical biosensors, maintains activity of the enzyme reagents by proper selection of components. A preferred composition includes hydrophilic polymers, amorphous untreated silica, buffers, surfactants, and a mediator. <P>COPYRIGHT: (C)2013,JPO&INPIT |