发明名称 |
Diagnostic Marker for Hepatocellular Carcinoma Comprising Anti-FASN Autoantibodies and a Diagnostic Composition for Hepatocellular Carcinoma Comprising Antigens Thereof |
摘要 |
The present invention relates to an autoantibody specifically recognizing the epitope sequence of FASN (fatty acid synthase), more particularly, to the autoantibody or a fragment comprising an antigen-binding site thereof, a diagnostic composition for hepatocellular carcinoma comprising an agent capable of assessing the expression level of the autoantibody, a hybridoma cell line producing the autoantibody, a diagnostic kit for hepatocellular carcinoma comprising the composition, a method for detecting the autoantibody of hepatocellular carcinoma patient using the composition, and a method for screening a therapeutic agent for hepatocellular carcinoma by administering candidate materials for hepatocellular carcinoma treatment to confirm a reduction in the expression level of autoantibody.
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申请公布号 |
US2012264147(A1) |
申请公布日期 |
2012.10.18 |
申请号 |
US201013501426 |
申请日期 |
2010.10.01 |
申请人 |
CHO EUN WIE;HEO CHANG KYU;WOO MI KYUNG;HWANG HAI MIN;YOO HYANG SOOK;KO JEONG HEUN;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
CHO EUN WIE;HEO CHANG KYU;WOO MI KYUNG;HWANG HAI MIN;YOO HYANG SOOK;KO JEONG HEUN |
分类号 |
G01N33/574;C07K7/06;C07K16/40;C12N5/20;G01N21/64;G01N33/558;G01N33/559;G01N33/561;G01N33/566 |
主分类号 |
G01N33/574 |
代理机构 |
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