| 发明名称 |
BCHE ALBUMIN FUSIONS FOR THE TREATMENT OF COCAINE ABUSE |
| 摘要 |
<p>A method of attenuating a biological effect of cocaine exposure in a primate. Such method includes administering to the primate an amount of a BChE-albumin fusion protein comprising the amino acid substitutions A227S, S315G, A356W, and Y360G, wherein the amount of the fusion protein is effective to cause attenuation of the biological effect of cocaine exposure in the primate.</p> |
| 申请公布号 |
EP2509616(A1) |
申请公布日期 |
2012.10.17 |
| 申请号 |
EP20100836553 |
申请日期 |
2010.12.07 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
SKLAIR-TAVRON, LIORA;ROSENSTOCK, MOTI;SHEMESH-DARVISH, LIRON;HALLAK, HUSSEIN;PIRYATINSKY, VICTOR;ROSCHKE, VIKTOR;LAFLEUR, DAVID |
| 分类号 |
A61K38/16;A61K38/38;A61K38/46;A61P25/30 |
主分类号 |
A61K38/16 |
| 代理机构 |
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代理人 |
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