| 发明名称 |
siRNA specific to WT1 17AA(−)isoform and use thereof |
| 摘要 |
Disclosed is a polynucleotide having at least 15 contiguous bases in the base sequence of SEQ ID NO:26 and including the base sequence of SEQ ID NO:27. Also disclosed is siRNA produced based on the polynucleotide. By means of this, a cancer cell-specific molecular-targeted therapy, which successfully controls the function of WT1, can be realized. |
| 申请公布号 |
US8288355(B2) |
申请公布日期 |
2012.10.16 |
| 申请号 |
US20070225745 |
申请日期 |
2007.03.28 |
| 申请人 |
SUGIYAMA HARUO;OJI YUSUKE;INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. |
发明人 |
SUGIYAMA HARUO;OJI YUSUKE |
| 分类号 |
C07H21/02;C12N15/00;C12N15/113 |
主分类号 |
C07H21/02 |
| 代理机构 |
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| 主权项 |
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