发明名称 STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS
摘要 A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).
申请公布号 CA2557324(C) 申请公布日期 2012.10.16
申请号 CA20052557324 申请日期 2005.02.28
申请人 OSTEOLOGIX A/S 发明人 HANSEN, CHRISTIAN;NILSSON, HENRIK;CHRISTGAU, STEPHAN;BONE, HENRY G., III
分类号 A61K33/24;A61K31/28;A61K31/56;A61K31/57;A61K31/663;A61K45/06 主分类号 A61K33/24
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