| 摘要 |
PURPOSE: An eco-friendly synthesis method for 2,3-dihydroquinazole derivatives and spiro-oxindole derivatives thereof is provided to be usefully applied for mass synthesis. CONSTITUTION: A synthesis method for 2,3-dihydroquinazolinone derivative of chemical formula 1 comprises: a step of reacting isatoic anhydride, amines, and benzaldehydes in water under the presence of EDDA(ethylenediamine diacetate). The synthesis method for 2,3-dihydroquinazolinone derivative of chemical formula 2 comprises a step of reacting isatoic anhydride, amines, and istins in water under the presence of EDDA.
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