发明名称 |
METHOD FOR DIAGNOSING INFLAMMATORY DISEASES THROUGH ANALYSIS OF PROTEIN OR GENE OF EXTRACELLULAR VESICLE IN A BODY FLUID |
摘要 |
PURPOSE: A method for diagnosing inflammatory diseases and a diagnosis kit are provided to improve diagnosis accuracy. CONSTITUTION: A method for diagnosing inflammatory diseases comprises: a step of isolating cell adhesion proteins in fluid into water soluble protein fraction and extracellular endoplasmic reticulum fraction; and a step of quantitating proteins in the water soluble protein fraction and extracellular endoplasmic reticulum fraction. The proteins contain ICAM-1(intercellular adhesion molecule-1), E-selectin, and VCAM-1(vascular cell adhesion molecule-1). A method for diagnosing inflammatory diseases comprises a step of measuring the expression level of gene existing in the extracellular endoplasmic reticulum of body fluid. The cell adhesion protein is ICAM-1, E-selectin, and VCAM-1. [Reference numerals] (AA,EE) Cell culture liquid; (BB) Ultracentrifugation; (CC,FF) Soluble protein; (DD,GG) Extracellular endoplasmic reticulum |
申请公布号 |
KR20120111788(A) |
申请公布日期 |
2012.10.11 |
申请号 |
KR20110029195 |
申请日期 |
2011.03.31 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
GHO, YONG SONG;KIM, YOON KEUN;CHOI, EUN JEONG;YOON, YAE JIN;JANG, SU CHUL |
分类号 |
G01N33/68;C12N15/12;C12Q1/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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